Pleural effusion
Incidental findings Clubbing, radiation burns, aspiration marks, lymphadenopathy
+ve signs Stony dull PN, ↓breath sounds, ↓vocal resonance
Differential diagnosis Pleural effusion cause depends upon transudate or exudate
Function ?respiratory compromise
Tests CXR, USS
Pleural tap – protein, albumin, LDH, glucose, cyto, micro, AFB
Pleural biopsy, CT chest
Causes

Transudate
Cardiac failure
Nephrotic syndrome
Cirrhosis
Exudate
Neoplastic: Ca bronchus / met / mesothelioma
Infectious: Pneumonia, TB
Connective tissue: RA, SLE
PE
Notes

  • Protein > 30 = exudate, protein < 30 = transudate
  • Lights criteria for exudate (i) pleural:serum protein > 0.5 (ii) pleural:serum LDH > 0.6 (iii) pleural LDH > ⅔ upper limit for serum LDH
  • Serum:effusion albumin gradient 1.2g/dl very specific for exudate
  • Can have area of bronchial breathing above dullness. c.f. Consolidation = bronchial breathing, increased vocal resonance; Collapse = trachea to side, absent breath sounds.
  • Meigs = Ovarian tumour with R effusion (transudate)